Markers of Oxidative Stress during Diabetes Mellitus
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چکیده
منابع مشابه
Markers of Oxidative Stress during Diabetes Mellitus
The prevalence of diabetes mellitus is rising all over the world. Uncontrolled state of hyperglycemia due to defects in insulin secretion/action leads to a variety of complications including peripheral vascular diseases, nephropathy, neuropathy, retinopathy, morbidity, and/or mortality. Large body of evidence suggests major role of reactive oxygen species/oxidative stress in development and pro...
متن کاملOxidative Stress in Diabetes Mellitus
Our aim was to evaluate oxidative stress in diabetes mellitus by the measurement of biophysical parameters (changes) of hemoglobin macromolecule and some biochemical parameters on two groups of diabetic patients, non-insulin dependent diabetes mellitus (NIDDM), and insulindependent diabetes mellitus (IDDM). This study has been conducted on 45 NIDDM, 30 IDDM, compared to 20 healthy subjects. Blo...
متن کاملOxidative stress in diabetes mellitus
Oxidative stress is the outcome of an imbalance between the production and neutralization of reactive oxygen and nitrogen species (RONS) such that the antioxidant capacity of cell is overwhelmed. The present review briefly summarized the underlying role of overwhelming levels of RONS in the pathophysiology of diabetes mellitus (DM). The primary causative factor of oxidative stress in DM is hype...
متن کاملOxidative lipid, protein, and DNA damage as oxidative stress markers in vascular complications of diabetes mellitus.
PURPOSE The purpose of this study was to determine the effects of diabetic complications on oxidation of proteins, lipids, and DNA and to investigate the relationship between oxidative damage markers and clinical parameters. METHODS The study group consisted of 69 type 2 diabetic patients (20 patients without complication, 49 patients with complication) who attended internal medicine outpatie...
متن کاملIncreased breath biomarkers of oxidative stress in diabetes mellitus.
BACKGROUND Oxidative stress has been implicated in the major complications of diabetes mellitus, including retinopathy, nephropathy, neuropathy and accelerated coronary artery disease. There is a clinical need for a marker of oxidative stress which could potentially identify diabetic patients at increased risk for these complications. We measured oxidative age, a new breath marker of oxidative ...
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ژورنال
عنوان ژورنال: Journal of Biomarkers
سال: 2013
ISSN: 2090-8660,2090-7699
DOI: 10.1155/2013/378790